There’s something incredibly comforting about a slow-cooked meatball dish, and Mississippi meatballs are no exception. The first time I made them, I was amazed at how such a simple recipe could pack such bold flavors. The combination of savory meatballs, zesty ranch seasoning, and a hint of spice from pepperoncini made this dish an instant favorite in my home. Whether you’re serving them over mashed potatoes, rice, or in a sandwich, this Mississippi meatballs recipe is sure to become a go-to comfort meal.
Ingredients for Mississippi Meatballs
For the Meatballs:
- 1 ½ lbs ground beef (or a mix of beef and pork)
- ½ cup breadcrumbs
- 1 egg
- 2 tablespoons milk
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- ½ teaspoon salt
- ½ teaspoon black pepper
For the Sauce:
- 1 packet ranch seasoning mix
- 1 packet au jus gravy mix
- ½ cup unsalted butter (1 stick)
- ½ cup beef broth
- 6-8 pepperoncini peppers (plus 2 tablespoons of juice)
- 1 teaspoon Worcestershire sauce (optional)
How to make Mississippi Meatballs?
Step 1: Prepare the Meatballs
- In a large mixing bowl, combine ground beef, breadcrumbs, egg, milk, garlic powder, onion powder, salt, and black pepper.
- Mix well and shape into 1-inch meatballs. Place them on a parchment-lined baking sheet.
- Bake at 400°F (200°C) for 15 minutes, or until browned. Alternatively, you can pan-sear them for a crispier texture.
Step 2: Prepare the Sauce
- In a slow cooker or large pot, add the beef broth, ranch seasoning, au jus mix, butter, and pepperoncini (including the juice).
- Stir until well combined.
Step 3: Cook the Meatballs
- Add the browned meatballs to the sauce, ensuring they are fully coated.
- Cover and cook on low for 4-6 hours (or on high for 2-3 hours) in a slow cooker. If cooking on the stovetop, let them simmer for 30-40 minutes on low heat.
- Stir occasionally to prevent sticking.
Step 4: Serve and Enjoy!
Serve the Mississippi meatballs over mashed potatoes, rice, egg noodles, or as a sandwich filling. Garnish with extra pepperoncini for added zest!
Why You’ll Love Mississippi Meatballs Recipe
✔ Easy to Make: Simple ingredients and minimal prep time.
✔ Packed with Flavor: The combination of ranch, au jus, and pepperoncini creates a bold, tangy, and savory taste.
✔ Perfect for Meal Prep: Make ahead and store for easy lunches or dinners.
✔ Versatile: Serve over carbs, on sandwiches, or as an appetizer
Final Thoughts On Mississippi Meatballs
If you love comfort food with a punch of bold flavors, this Mississippi meatballs recipe is a must-try. Whether you serve them for a cozy family dinner or as a party appetizer, they’re sure to impress! Try it out and let us know how you enjoyed it. Happy cooking! 🍽️✨
Mississippi Meatballs Recipe: A Flavorful Southern Classic
These Mississippi Meatballs are the perfect blend of savory, tangy, and buttery goodness! Made with tender meatballs slow-cooked in a rich and flavorful sauce, this easy recipe is a must-try for busy weeknights or party appetizers. Get ready to impress your taste buds with every bite!

Ingredients
For the Meatballs
For the Sauce
Instructions
-
Step 1: Prepare the Meatballs
-
In a large mixing bowl, combine ground beef, breadcrumbs, egg, milk, garlic powder, onion powder, salt, and black pepper.
-
Mix well and shape into 1-inch meatballs. Place them on a parchment-lined baking sheet.
-
Bake at 400°F (200°C) for 15 minutes, or until browned. Alternatively, you can pan-sear them for a crispier texture.
-
Step 2: Prepare the Sauce
-
In a slow cooker or large pot, add the beef broth, ranch seasoning, au jus mix, butter, and pepperoncini (including the juice).
-
Stir until well combined.
-
Step 3: Cook the Meatballs
-
Add the browned meatballs to the sauce, ensuring they are fully coated.
-
Cover and cook on low for 4-6 hours (or on high for 2-3 hours) in a slow cooker. If cooking on the stovetop, let them simmer for 30-40 minutes on low heat.
-
Stir occasionally to prevent sticking.
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Step 4: Serve and Enjoy!
Nutrition Facts
- Amount Per Serving
- Calories 280kcal
- % Daily Value *
- Total Fat 20g31%
- Sodium 600mg25%
- Total Carbohydrate 8g3%
- Sugars 5g
- Protein 18g36%
* Percent Daily Values are based on a 2,000 calorie diet. Your daily value may be higher or lower depending on your calorie needs.